BDBM228073 US9556160, ex 74

SMILES NC(=N)CC(=O)OCc1cccc(c1F)-c1cnc(OCC2CCN(CC2)C(=O)C2CC2)nc1

InChI Key InChIKey=VMEGJOLGMHSJGI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 228073   

TargetAmine oxidase [copper-containing] 3(Human)
Astellas Pharma

US Patent
LigandPNGBDBM228073(US9556160, ex 74)
Affinity DataIC50: 5.30nMT: 2°CAssay Description:A human VAP-1 enzyme (SSAO) (reference: J Exp Med. 1998 Jul. 6; 188(1): 17 to 27) activity was measured by a radiochemistry-enzymatic assay using 14C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
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TargetMembrane primary amine oxidase(Rat)
Astellas Pharma

US Patent
LigandPNGBDBM228073(US9556160, ex 74)
Affinity DataIC50: 1.80nMT: 2°CAssay Description:A rat VAP-1 enzyme (SSAO) (reference: Biol Pharm Bull. 2005 March; 28(3): 413-8) activity was measured by a radiochemistry-enzymatic assay using 14C-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2018
Entry Details
Go to US Patent