BDBM22978 2-[(2,6-dichloro-3-methylphenyl)amino]-N-(2-phenylethyl)benzamide::CHEMBL149134::Meclofenamic acid derivative, 30

SMILES Cc1ccc(Cl)c(Nc2ccccc2C(=O)NCCc2ccccc2)c1Cl

InChI Key InChIKey=KQUGWHSHDAHRQE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22978   

TargetProstaglandin G/H synthase 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22978(CHEMBL149134 | 2-[(2,6-dichloro-3-methylphenyl)ami...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

LigandPNGBDBM22978(CHEMBL149134 | 2-[(2,6-dichloro-3-methylphenyl)ami...)
Affinity DataIC50: 4.00E+3nMpH: 8.0 T: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Vanderbilt University School of Medicine

LigandPNGBDBM22978(CHEMBL149134 | 2-[(2,6-dichloro-3-methylphenyl)ami...)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of the ovine Prostaglandin G/H synthase 1 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22978(CHEMBL149134 | 2-[(2,6-dichloro-3-methylphenyl)ami...)
Affinity DataIC50: 4.50E+3nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2008
Entry Details Article
PubMed