BDBM23061 7-(3-chlorophenyl)-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]heptan-1-one::CHEMBL388599::alpha-ketooxazole, 5hh

SMILES Clc1cccc(CCCCCCC(=O)c2ncc(o2)-c2ccccn2)c1

InChI Key InChIKey=AJTFTOJFTFVQHK-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23061   

TargetCarboxylic ester hydrolase(Human)
The Scripps Research Institute

LigandPNGBDBM23061(CHEMBL388599 | 7-(3-chlorophenyl)-1-[5-(pyridin-2-...)
Affinity DataIC50: 500nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2008
Entry Details Article
PubMed
TargetDNA ligase 1(Human)
The Scripps Research Institute

LigandPNGBDBM23061(CHEMBL388599 | 7-(3-chlorophenyl)-1-[5-(pyridin-2-...)
Affinity DataKi:  0.900nM ΔG°:  -12.3kcal/mole IC50: 2nMT: 2°CAssay Description:The inhibition assays were performed by incubating enzyme, 14C-labeled oleamide in reaction buffer at room temperature in the presence of three diffe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2008
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM23061(CHEMBL388599 | 7-(3-chlorophenyl)-1-[5-(pyridin-2-...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed