BDBM230936 US10188642, Example 62::US9334286, 62

SMILES COCCNC(=O)c1ccc(Nc2cc3cc(ccc3cn2)-c2cnn(CC(C)(C)O)c2)c(OC)c1

InChI Key InChIKey=XRJAIBLGIJGYBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 230936   

TargetDual specificity protein kinase TTK(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM230936(US9334286, 62 | US10188642, Example 62)
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM230936(US9334286, 62 | US10188642, Example 62)
Affinity DataIC50: 3nMAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2019
Entry Details
Go to US Patent