BDBM2311 1,5-Diphenyl-3-methylpyrazole (DPP) analogue::2-(3-methyl-1,5-diphenyl-1H-pyrazol-4-yl)acetonitrile::PNU-32945

SMILES Cc1nn(c(c1CC#N)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=DSWZCGSZXQUWRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2311   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2311(1,5-Diphenyl-3-methylpyrazole (DPP) analogue | 2-(...)
Affinity DataIC50: 2.31E+3nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2004
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,P823L]/[588-1147,P823L](Human immunodeficiency virus type 1)
Upjohn

LigandPNGBDBM2311(1,5-Diphenyl-3-methylpyrazole (DPP) analogue | 2-(...)
Affinity DataIC50: 1.14E+3nMpH: 8.3 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2004
Entry Details Article
PubMed