BDBM232218 N-4-fluorobenzoyl-L-leucine-glycine nitrile (14)

SMILES CCC(C)[C@H](NC(=O)c1ccc(F)cc1)C(=O)NCC#N

InChI Key InChIKey=KLGWPFGHTSXZNV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 232218   

TargetSecreted cathepsin L 1(Liver fluke)
Dublin City University

LigandPNGBDBM232218(N-4-fluorobenzoyl-L-leucine-glycine nitrile (14))
Affinity DataIC50: 2.80E+3nMAssay Description:The protease was activated by the addition of dithiothreitol, ethylenediaminetetraacetic acid (EDTA), and sodium acetate followed by incubation at 37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/9/2017
Entry Details Article
PubMed