BDBM23307 2-[(2-cyclohexylquinazolin-4-yl)sulfanyl]-N-(furan-2-ylmethyl)acetamide::Compound PJ07::acs.jmedchem.1c00409_ST.596::jm5b01461, Compound 182

SMILES O=C(CSc1nc(nc2ccccc12)C1CCCCC1)NCc1ccco1

InChI Key InChIKey=TUMJQFRANSTLTQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 23307   

TargetReplicase polyprotein 1ab(SARS-CoV)
University of Mississippi

LigandPNGBDBM23307(2-[(2-cyclohexylquinazolin-4-yl)sulfanyl]-N-(furan...)
Affinity DataIC50: 1.82E+4nMpH: 7.4 T: 2°CAssay Description:The effects of compound on enzyme activity were measured by using a fluorogenic peptide cleavage assay. Enhanced fluorescence caused by cleavage of t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/8/2008
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Mississippi

LigandPNGBDBM23307(2-[(2-cyclohexylquinazolin-4-yl)sulfanyl]-N-(furan...)
Affinity DataIC50: 1.82E+4nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Mississippi

LigandPNGBDBM23307(2-[(2-cyclohexylquinazolin-4-yl)sulfanyl]-N-(furan...)
Affinity DataIC50: 1.82E+4nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed