BDBM233398 US9351965, 5::US9351965, 6::US9351965, 7::US9351965, 8

SMILES Cc1cc(ccn1)-c1n[nH]c2ccc(cc12)C(=O)NC1CCCC(O)(Cc2c(F)cccc2F)C1

InChI Key InChIKey=KQGOMZCPHNSIAO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 233398   

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233398(US9351965, 8 | US9351965, 7 | US9351965, 6 | US935...)
Affinity DataIC50: 1.00E+3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233398(US9351965, 8 | US9351965, 7 | US9351965, 6 | US935...)
Affinity DataIC50: 1.00E+3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233398(US9351965, 8 | US9351965, 7 | US9351965, 6 | US935...)
Affinity DataIC50: 15.2nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233398(US9351965, 8 | US9351965, 7 | US9351965, 6 | US935...)
Affinity DataIC50: 1.00E+3nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent