BDBM233432 US9351965, 39::US9351965, 40

SMILES COC1(Cc2ccccc2F)CCCC(C1)NC(=O)c1ccc2[nH]nc(-c3ccnc(C)c3)c2c1

InChI Key InChIKey=OZVRHJXXYSRZDT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 233432   

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233432(US9351965, 40 | US9351965, 39)
Affinity DataIC50: 28.5nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase 1(Mouse)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM233432(US9351965, 40 | US9351965, 39)
Affinity DataIC50: 205nMAssay Description:Activated ERK2 activity was also determined in the IMAP assay format using the procedure outlined above. 1 μl of 25× compound was added to 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent