BDBM233854 US9353081, 58::US9353081, 59::US9353081, 60

SMILES CCC(=O)NC1CCc2c1cncc2-c1cc(Cl)c2N(C)C(=O)CCc2c1

InChI Key InChIKey=VAPHWOXHHBPQER-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 233854   

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM233854(US9353081, 59 | US9353081, 60 | US9353081, 58)
Affinity DataEC50:  8.80nMT: 2°CAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM233854(US9353081, 59 | US9353081, 60 | US9353081, 58)
Affinity DataEC50:  44.6nMT: 2°CAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM233854(US9353081, 59 | US9353081, 60 | US9353081, 58)
Affinity DataEC50:  1.17E+3nMT: 2°CAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetCytochrome P450 11B2, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM233854(US9353081, 59 | US9353081, 60 | US9353081, 58)
Affinity DataEC50:  3.29E+3nMT: 2°CAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent

TargetCytochrome P450 11B1, mitochondrial(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM233854(US9353081, 59 | US9353081, 60 | US9353081, 58)
Affinity DataEC50:  7.60E+3nMT: 2°CAssay Description:The expression plasmids contains the ORF for either human/cyno CYP11B1 or CYP11B2 under the control of a suitable promoter (CMV-promoter) and a suita...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
US Patent