BDBM234270 4-oxo-β-lactam (3)

SMILES CCC1(CC)C(=O)N(C1=O)c1ccc(CS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=KDYDIDDYWKCQJA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 234270   

TargetNeutrophil elastase(Human)
University of Lisbon

LigandPNGBDBM234270(4-oxo-β-lactam (3))
Affinity DataKi:  0.630nM ΔG°:  -12.5kcal/moleT: 2°CAssay Description:The inhibition of the HLE was studied at 25°C by continuously monitoring the absorbance at 410 nm for 20 min of a solution prepared by mixing 10 _...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details Article
PubMed