BDBM234349 2,3,6,7,8,9-Hexahydro-benzothieno[2,3-d]-imidazo[1,2-a]pyrimidin-5(11H)-one (7)

SMILES O=C1N2CCN=C2Nc2sc3CCCCc3c12

InChI Key InChIKey=ZWUHKTPOXYDZFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 234349   

TargetAcetylcholinesterase(Electric eel)
University of Bonn

LigandPNGBDBM234349(2,3,6,7,8,9-Hexahydro-benzothieno[2,3-d]-imidazo[1...)
Affinity DataIC50: 7.50E+4nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bonn

LigandPNGBDBM234349(2,3,6,7,8,9-Hexahydro-benzothieno[2,3-d]-imidazo[1...)
Affinity DataIC50: 2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bonn

LigandPNGBDBM234349(2,3,6,7,8,9-Hexahydro-benzothieno[2,3-d]-imidazo[1...)
Affinity DataIC50: 2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed