BDBM234350 2,3,4,7,8,9,10,12-Octahydro-6H-benzothieno[2,3-d]pyrimido[1,2-a]pyrimidin-6-one (8)

SMILES O=C1N2CCCN=C2Nc2sc3CCCCc3c12

InChI Key InChIKey=CCUQDOQOUHWYDI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 234350   

TargetAcetylcholinesterase(Electric eel)
University of Bonn

LigandPNGBDBM234350(2,3,4,7,8,9,10,12-Octahydro-6H-benzothieno[2,3-d]p...)
Affinity DataIC50: 7.50E+4nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bonn

LigandPNGBDBM234350(2,3,4,7,8,9,10,12-Octahydro-6H-benzothieno[2,3-d]p...)
Affinity DataIC50: 2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Bonn

LigandPNGBDBM234350(2,3,4,7,8,9,10,12-Octahydro-6H-benzothieno[2,3-d]p...)
Affinity DataIC50: 2.00E+5nMpH: 7.3 T: 2°CAssay Description:Cholinesterase inhibition was assayed spectrophotometrically at 412 nm at 25°C [Pietsch et al., J. Med. Chem., 48:8270-8288; Ellman et al., Bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2017
Entry Details Article
PubMed