BDBM235660 3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (4a)

SMILES O=c1oc2ccccc2cc1-c1nnc(o1)-c1ccccc1

InChI Key InChIKey=XCWSXFUBKNIMTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235660   

TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235660(3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235660(3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (...)
Affinity DataIC50: 8.70E+3nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed