BDBM235661 3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chromen-2-one (4b)

SMILES Clc1ccc(cc1)-c1nnc(o1)-c1cc2ccccc2oc1=O

InChI Key InChIKey=BKSIRJBXYHOZTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 235661   

TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235661(3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chro...)
Affinity DataIC50: 3.50E+4nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235661(3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chro...)
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed