BDBM23621 2-({6-[(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-yl)pyrimido[5,4-d][1,3]diazin-2-yl}amino)ethan-1-ol::Dipyridamole Analogue, 1

SMILES OCCNc1nc(N2CCCCC2)c2nc(NCCO)nc(N3CCCCC3)c2n1

InChI Key InChIKey=PNNHNKCEAAYNQD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23621   

TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23621(2-({6-[(2-hydroxyethyl)amino]-4,8-bis(piperidin-1-...)
Affinity DataKi:  691nM ΔG°:  -8.31kcal/mole IC50: 1.22E+4nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed