BDBM23624 2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(morpholin-4-yl)pyrimido[5,4-d][1,3]diazin-2-yl}(2-hydroxyethyl)amino)ethan-1-ol::Dipyridamole Analogue, 4

SMILES OCCN(CCO)c1nc(N2CCOCC2)c2nc(nc(N3CCOCC3)c2n1)N(CCO)CCO

InChI Key InChIKey=DTGJNCXRSGBFNE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 23624   

TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Science Center

LigandPNGBDBM23624(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(morpholin...)
Affinity DataKi:  393nM ΔG°:  -8.64kcal/mole IC50: 6.96E+3nMpH: 7.4 T: 2°CAssay Description:The compounds were tested to determine their ENT1 nucleoside transporter binding ability by a flow cytometric assay using human leukemia K562 cells i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed