BDBM237218 1-(2, 4-Difluorophenyl)-1-(4-hydroxy-3-methoxybenzyl)-3-phenylurea (10a)

SMILES COc1cc(CN(C(=O)Nc2ccccc2)c2ccc(F)cc2F)ccc1O

InChI Key InChIKey=UXLRQUMLKCUUBY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 237218   

TargetMitogen-activated protein kinase 1/3(Human)
Nanjing University

LigandPNGBDBM237218(1-(2, 4-Difluorophenyl)-1-(4-hydroxy-3-methoxybenz...)
Affinity DataIC50: 6.47E+3nMAssay Description:Detection of the effect of compounds on p-MEK1/2, t-ERK1/2, pERK1/2, p-Rsk1 and p-Elk-1 activity in B16-F10 cells was performed using ELISA kits (Inv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed