BDBM23766 3-{[4-(4-hexadecylpiperazin-1-yl)phenyl]methyl}-4,5-dihydro-1,2,4-oxadiazol-5-one::PMS 1062 piperazine deriv., 27b

SMILES CCCCCCCCCCCCCCCCN1CCN(CC1)c1ccc(Cc2nc(=O)o[nH]2)cc1

InChI Key InChIKey=GECFBNZUIZKPOM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 23766   

TargetPhospholipase A2, membrane associated(Human)
Universite Paris 7-Denis Diderot

LigandPNGBDBM23766(3-{[4-(4-hexadecylpiperazin-1-yl)phenyl]methyl}-4,...)
Affinity DataIC50: 3.50E+3nMpH: 7.5 T: 2°CAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed
TargetPhospholipase A2, major isoenzyme(Pig)
Universite Paris 7-Denis Diderot

LigandPNGBDBM23766(3-{[4-(4-hexadecylpiperazin-1-yl)phenyl]methyl}-4,...)
Affinity DataIC50: 1.00E+5nMAssay Description:PLA2 activity is by using the fluorescent phospholipid analogue, beta-pyC-10-PG as the substrate. The increase in fluorescence (ex @342 nm and em@388...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2008
Entry Details Article
PubMed