BDBM238051 US9394285, 139

SMILES OCCOc1ccc(cc1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O

InChI Key InChIKey=YGKWXCWHOYVSAU-UHFFFAOYSA-N

Data  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 238051   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM238051(US9394285, 139)Copy SMILESCopy InChI

Affinity DataEC50:  47nMAssay Description:Allosteric activation of human AMPK alpha1/beta1/gamma1 by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
10/24/2019
Entry Details Article
Copy BDB DOIPubMed
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Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Human)
Pfizer

Curated by ChEMBL

LigandBDBM238051(US9394285, 139)Copy SMILESCopy InChI

Affinity DataEC50:  72.8nMpH: 7.5 T: 2°CAssay Description:The biochemical EC50 (half-maximal concentration required for full activation) of compounds for the activation of AMPK was evaluated by 33P-based ass...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
7/17/2017
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL