BDBM238190 US9394303, 16

SMILES Cc1nn(Cc2ccc(Oc3ccccc3)cc2)c2nc(\C=C\c3ccccc3)cc(C(O)=O)c12

InChI Key InChIKey=GJQROVAAOLUDGL-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 238190   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1 homolog(Mouse)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238190(US9394303, 16)
Affinity DataKi:  210nM ΔG°:  -9.10kcal/mole IC50: 1.11E+3nMpH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2(Mouse)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238190(US9394303, 16)
Affinity DataKi:  3.16E+3nM ΔG°:  -7.50kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Mouse)
The Regents of The University of Michigan

US Patent
LigandPNGBDBM238190(US9394303, 16)
Affinity DataKi:  3.55E+3nM ΔG°:  -7.43kcal/molepH: 7.4 T: 2°CAssay Description:Sensitive and quantitative FP-based binding assays were developed and optimized to determine the binding affinities of small-molecule inhibitors to t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details
Go to US Patent