BDBM239062 US10227295, Compound 10b::US9409858, 10b

SMILES CC(C)[C@H]1N(Cc2ccc(cc2)C(=O)NO)C(=O)N(C1=O)c1ccccc1

InChI Key InChIKey=HCWWRBZVJKBTNV-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 239062   

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239062(US9409858, 10b | US10227295, Compound 10b)
Affinity DataIC50: 1.18E+4nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239062(US9409858, 10b | US10227295, Compound 10b)
Affinity DataIC50: 22.2nMpH: 8.0Assay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239062(US9409858, 10b | US10227295, Compound 10b)
Affinity DataIC50: 1.18E+4nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM239062(US9409858, 10b | US10227295, Compound 10b)
Affinity DataIC50: 22.2nMAssay Description:HDAC inhibition assays were performed by Reaction Biology Corp. (Malvern, Pa.) using isolated human, recombinant full-length HDAC1 and -6 from a bacu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
Go to US Patent