BDBM2403 Pyrrolyl Aryl Sulfone (PAS) 24::ethyl 1-[(2-amino-5-chlorobenzene)sulfonyl]-4-(phenoxymethyl)-1H-pyrrole-2-carboxylate

SMILES CCOC(=O)c1cc(COc2ccccc2)cn1S(=O)(=O)c1cc(Cl)ccc1N

InChI Key InChIKey=ATZCDBKPHXPNRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 2403   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Sapienza University of Rome

LigandPNGBDBM2403(ethyl 1-[(2-amino-5-chlorobenzene)sulfonyl]-4-(phe...)
Affinity DataIC50: 600nMpH: 7.8 T: 2°CAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2004
Entry Details Article
PubMed