BDBM24032 (2S)-3-methyl-2-[(4-phenylbenzene)sulfonamido]butanoic acid::CHEMBL43147::biphenylsulfonamide carboxylate, 9

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(O)=O

InChI Key InChIKey=BGKNBDGHNBOSGD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 24032   

LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:The recombinant Agg-1 proteins pretreated with the various concentrations of the compound for 10 to 15 min. The reaction was initiated by addition of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2008
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 5.40E+3nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 38nMAssay Description:In vitro inhibition of recombinant human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 2.60E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 62nMAssay Description:In vitro inhibition of human recombinant matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 40nMAssay Description:In vitro inhibition of matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 7.10E+4nMAssay Description:In vitro inhibition of matrix metalloprotease-7 (MMP-7)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/24/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Parke-Davis Pharmaceutical Research

Curated by ChEMBL
LigandPNGBDBM24032(CHEMBL43147 | (2S)-3-methyl-2-[(4-phenylbenzene)su...)
Affinity DataIC50: 2.57E+4nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed