BDBM241211 US11046688, Example 53::US9409907, 53

SMILES COc1cc(ccc1Nc1ncc2ccnc(OCC3CC3)c2n1)-c1cnn(C)c1

InChI Key InChIKey=BWHUMVAWMHVYPY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 241211   

TargetDual specificity protein kinase TTK(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM241211(US9409907, 53 | US11046688, Example 53)
Affinity DataIC50: 98nMpH: 7.0 T: 2°CAssay Description:The enzyme reaction (total volume 10 μl) was carried out in black 384-well low volume plates containing full length MPS1 (12.5 nM or 3 nM), fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details
Go to US Patent

TargetDual specificity protein kinase TTK(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM241211(US9409907, 53 | US11046688, Example 53)
Affinity DataIC50: 150nMAssay Description:Inhibition of human full length MPS1 expressed in recombinant baculovirus infected Sf9 insect cells using 5FAM-DHTGFLTEYVATRCONH2 as substrate after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/8/2017
Entry Details Article
PubMed