BDBM242431 US9422235, 4

SMILES COc1cc(Nc2ccc(c(c2)C(F)(F)F)S(=O)(=O)NCC2CC2)cc(OC)c1

InChI Key InChIKey=PXRZBSVMVTXTQV-UHFFFAOYSA-N

Data  9 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 242431   

TargetCannabinoid receptor 2(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  19nM ΔG°:  -10.7kcal/mole IC50: 37nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  29nM ΔG°:  -10.4kcal/mole IC50: 56nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  29.2nM ΔG°:  -10.4kcal/mole IC50: 58.1nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  34nM ΔG°:  -10.4kcal/mole IC50: 76nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 2(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  37nM ΔG°:  -10.3kcal/mole IC50: 68nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  260nM ΔG°:  -9.13kcal/mole IC50: 580nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  400nM ΔG°:  -8.87kcal/mole IC50: 720nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  1.16E+3nM ΔG°:  -8.23kcal/mole IC50: 2.00E+3nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent

TargetCannabinoid receptor 1(Human)
Pharmos

US Patent
LigandPNGBDBM242431(US9422235, 4)
Affinity DataKi:  1.56E+3nM ΔG°:  -8.05kcal/mole IC50: 3.06E+3nMT: 2°CAssay Description:The binding assays were performed by testing the ability of the new compounds to displace the radiolabeled synthetic non-selective cannabinoid agonis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2017
Entry Details
Go to US Patent