BDBM243078 17-Oxaandrost-5-ene-3β-yl-benzoate (1)

SMILES C[C@]12CCC3C(CC=C4C[C@H](CC[C@]34C)OC(=O)c3ccccc3)C1CCC2=O

InChI Key InChIKey=BNRQVKZXNLCKQZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 243078   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243078(17-Oxaandrost-5-ene-3β-yl-benzoate (1))
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
National University of Mexico City

LigandPNGBDBM243078(17-Oxaandrost-5-ene-3β-yl-benzoate (1))
Affinity DataIC50: 1.00E+5nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed