BDBM243079 17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2)

SMILES C[C@]12CCC3C(CC=C4C[C@H](CC[C@]34C)OC(=O)c3ccc(F)cc3)C1CCC2=O

InChI Key InChIKey=IUSJWDXQDRIDEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 243079   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
National University of Mexico City

LigandPNGBDBM243079(17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2...)
Affinity DataIC50: 3.58nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243079(17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2...)
Affinity DataIC50: 900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed