BDBM24354 N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-5-yl}phenyl)-N'-hydroxyoctanediamide::Triazole Ligand, 12b

SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)-c1cnnn1Cc1ccc(F)cc1

InChI Key InChIKey=ZKGHRYATLBNIFZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 24354   

TargetHistone deacetylase 6(Human)
University of Illinois At Chicago

LigandPNGBDBM24354(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50: 7.30nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Illinois At Chicago

LigandPNGBDBM24354(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50: 16.4nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Illinois At Chicago

LigandPNGBDBM24354(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50: 52.4nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Illinois At Chicago

LigandPNGBDBM24354(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50: 57.4nMpH: 7.5 T: 2°CAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Illinois At Chicago

LigandPNGBDBM24354(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50: 64.7nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Illinois At Chicago

LigandPNGBDBM24354(N-(4-{1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazol-...)
Affinity DataIC50: 2.01E+3nMAssay Description:The inhibitory effects of compounds on histone deacetylase (HDAC) activity were determined using a fluorescence-based assay with electrophoretic sepa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed