BDBM24378 2-chloro-N-{1-[2-(4-hydroxypiperidin-1-yl)-2-oxoethyl]-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl}-6H-thieno[2,3-b]pyrrole-5-carboxamide::3,4-dihydro-2-quinolone (DHQ) derivative, 17

SMILES OC1CCN(CC1)C(=O)CN1C(=O)C(Cc2ccccc12)NC(=O)c1cc2cc(Cl)sc2[nH]1

InChI Key InChIKey=HEXMHSAEGLWGCJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24378   

TargetGlycogen phosphorylase, liver form(Human)
Astrazeneca

LigandPNGBDBM24378(2-chloro-N-{1-[2-(4-hydroxypiperidin-1-yl)-2-oxoet...)
Affinity DataIC50: 709nMpH: 7.2 T: 2°CAssay Description:The inhibitory activity of the test compounds against human recombinant glycogen phosphorylase a (GPa) was monitored using 96-well microplate format....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed