BDBM24412 5-methyl-N-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine::JMC521864 Compund DSM12::Triazolopyrimidine-Based Compound, 19

SMILES Cc1cc(Nc2ccccc2)n2ncnc2n1

InChI Key InChIKey=RLASLOLCTAMGCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24412   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Texas At Dallas

LigandPNGBDBM24412(JMC521864 Compund DSM12 | 5-methyl-N-phenyl-[1,2,4...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2008
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Plasmodium falciparum (isolate 3D7))
University of Texas At Dallas

LigandPNGBDBM24412(JMC521864 Compund DSM12 | 5-methyl-N-phenyl-[1,2,4...)
Affinity DataIC50: 2.00E+5nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [100-517](Plasmodium berghei (strain Anka))
University of Washington At Seattle

LigandPNGBDBM24412(JMC521864 Compund DSM12 | 5-methyl-N-phenyl-[1,2,4...)
Affinity DataIC50: 1.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Human)
University of Washington At Seattle

LigandPNGBDBM24412(JMC521864 Compund DSM12 | 5-methyl-N-phenyl-[1,2,4...)
Affinity DataIC50: 2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2009
Entry Details Article
PubMed