BDBM244130 US9428492, 7::US9428492, 7a::US9428492, 7b

SMILES Cc1nc(C(O)CC(F)(F)F)n(n1)-c1cc(nc(C)n1)N1CC(C1)c1nc2ccccc2n1C

InChI Key InChIKey=LORZRBSQCFAMOJ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 244130   

LigandPNGBDBM244130(US9428492, 7b | US9428492, 7a | US9428492, 7)
Affinity DataKi:  2.5nM ΔG°:  -11.7kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

LigandPNGBDBM244130(US9428492, 7b | US9428492, 7a | US9428492, 7)
Affinity DataKi:  3.20nM ΔG°:  -11.6kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

LigandPNGBDBM244130(US9428492, 7b | US9428492, 7a | US9428492, 7)
Affinity DataKi:  4.5nM ΔG°:  -11.4kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent