BDBM244133 US9428492, 8::US9428492, 8a::US9428492, 8b

SMILES CC(O)c1nc(C)nn1-c1cc(nc(n1)C(F)(F)F)N1CC(C1)c1nc2ccccc2n1C

InChI Key InChIKey=HBSKAAGRJYPJCT-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 244133   

LigandPNGBDBM244133(US9428492, 8b | US9428492, 8a | US9428492, 8)
Affinity DataKi:  0.530nM ΔG°:  -12.6kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

LigandPNGBDBM244133(US9428492, 8b | US9428492, 8a | US9428492, 8)
Affinity DataKi:  0.830nM ΔG°:  -12.4kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

LigandPNGBDBM244133(US9428492, 8b | US9428492, 8a | US9428492, 8)
Affinity DataKi:  1nM ΔG°:  -12.3kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent