BDBM244143 US9428492, 13

SMILES C[C@H](O)c1nc(C)nn1-c1cc(nc(C)n1)C1C[C@H]1c1nc2ccccc2n1C

InChI Key InChIKey=KJNPQKXNYILKNS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244143   

LigandPNGBDBM244143(US9428492, 13)
Affinity DataKi:  0.740nM ΔG°:  -12.4kcal/molepH: 7.2 T: 2°CAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent

TargetCytochrome P450 2C9(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM244143(US9428492, 13)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition assay using CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details
US Patent