BDBM24441 2-pyridone analogue, 13::N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-2-oxo-1-phenyl-1,2-dihydropyridine-3-carboxamide

SMILES Fc1cc(NC(=O)c2cccn(-c3ccccc3)c2=O)ccc1Oc1ccnc2[nH]ccc12

InChI Key InChIKey=XUKXSDZCMRYFRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24441   

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24441(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 1.90nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24441(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed