BDBM24456 N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}phenyl)-6-phenylpyridine-2-carboxamide::pyridine analogue, 47

SMILES Fc1cc(NC(=O)c2cccc(n2)-c2ccccc2)ccc1Oc1ccnc2[nH]ccc12

InChI Key InChIKey=PGLMTHFDBWHAIP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24456   

TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24456(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 470nMpH: 7.5 T: 2°CAssay Description:Kinase activity was assayed using baculovirus expressed GST-Met, and poly(Glu/Tyr) as the substrate. Dose response curves were generated to determine...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/16/2008
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM24456(N-(3-fluoro-4-{1H-pyrrolo[2,3-b]pyridin-4-yloxy}ph...)
Affinity DataIC50: 470nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed