BDBM24634 N-phenyl-1H-indazole-3-carboxamide::indazole amide, 13

SMILES O=C(Nc1ccccc1)c1n[nH]c2ccccc12

InChI Key InChIKey=XQJXNILPLUCHQG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 24634   

LigandPNGBDBM24634(N-phenyl-1H-indazole-3-carboxamide | indazole amid...)
Affinity DataIC50: 3.00E+3nMpH: 7.2 T: 2°CAssay Description:CDK2/cyclin A activity was determined using a radiometric assay to measure the incorporation of gamma-phosphate from [gamma-33P]-ATP into histone H1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/29/2008
Entry Details Article
PubMed
LigandPNGBDBM24634(N-phenyl-1H-indazole-3-carboxamide | indazole amid...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CDK2/cyclin A (unknown origin) by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2016
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM24634(N-phenyl-1H-indazole-3-carboxamide | indazole amid...)
Affinity DataIC50: 417nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system using 5-FAM-peptid...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM24634(N-phenyl-1H-indazole-3-carboxamide | indazole amid...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human N-terminal GST-tagged FLT3 cytoplasmic domain (564 to 993 residues) expressed in baculovirus expression system using fluorescence...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2017
Entry Details Article
PubMed