BDBM246463 US9447114, 24

SMILES Cn1c2sc(c(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O)-c1ccc(Cl)cc1

InChI Key InChIKey=SDJSPAJTAKXHNU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246463   

TargetShort transient receptor potential channel 5(Human)
Hydra Biosciences

US Patent
LigandPNGBDBM246463(US9447114, 24)
Affinity DataIC50: 242nMpH: 7.4 T: 2°CAssay Description:The commercially available HEK293/TREx line (Invitrogen) was stably transfected with a TRPC5 construct and screened by conventional calcium imaging t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent

TargetShort transient receptor potential channel 5(Human)
Hydra Biosciences

US Patent
LigandPNGBDBM246463(US9447114, 24)
Affinity DataIC50: 1.84nMpH: 7.2Assay Description:TRPC5 cells were induced 20-48 hours, removed from growth plates, and replated at low density (to attain good single-cell physical separation) on gla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details
Go to US Patent