BDBM246509 1-(4-Nitrophenyl)-3-(4-(1,3,7,7-tetramethyl-5-oxo-1,2,3,4,5,6,7,8-octahydroquinazolin-4-yl)phenyl)thiourea (4e)

SMILES CN1C(C2=C(CC(C)(C)CC2=O)N(C)C1=O)c1ccc(NC(=S)Nc2ccc(cc2)[N+]([O-])=O)cc1

InChI Key InChIKey=KGRNQSCNEXLPEZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 246509   

TargetCarbonic anhydrase 2(Human)
Sakarya University

LigandPNGBDBM246509(1-(4-Nitrophenyl)-3-(4-(1,3,7,7-tetramethyl-5-oxo-...)
Affinity DataIC50: 1.55E+5nMAssay Description:For the inhibition studies of sulphanilamide, different concentrationsof these compounds were added to the enzyme. Activity percentage values of CA f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Sakarya University

LigandPNGBDBM246509(1-(4-Nitrophenyl)-3-(4-(1,3,7,7-tetramethyl-5-oxo-...)
Affinity DataIC50: 1.98E+5nMAssay Description:For the inhibition studies of sulphanilamide, different concentrationsof these compounds were added to the enzyme. Activity percentage values of CA f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2017
Entry Details Article
PubMed