BDBM248070 4-Methyl-2H-benzo[g]chromen-2-one (5)

SMILES Cc1cc(=O)oc2cc3ccccc3cc12

InChI Key InChIKey=SHQGYSUODYLEJI-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 248070   

TargetCarbonic anhydrase 9(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi:  200nM ΔG°:  -8.49kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi:  3.30E+3nM ΔG°:  -6.95kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi:  8.20E+3nM ΔG°:  -6.45kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi: >2.00E+5nM ΔG°: >-4.69kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed