BDBM24869 3-ethyl-1-[1-({4-[2-(methylsulfanyl)-6-phenylpyrido[2,3-d]pyrimidin-7-yl]phenyl}methyl)piperidin-4-yl]urea::Pyridopyrimidine, 13b

SMILES CCNC(=O)NC1CCN(Cc2ccc(cc2)-c2nc3nc(SC)ncc3cc2-c2ccccc2)CC1

InChI Key InChIKey=HOMHJTJWACGWMP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24869   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM24869(3-ethyl-1-[1-({4-[2-(methylsulfanyl)-6-phenylpyrid...)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2008
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

LigandPNGBDBM24869(3-ethyl-1-[1-({4-[2-(methylsulfanyl)-6-phenylpyrid...)
Affinity DataIC50: 1.91E+3nMAssay Description:Purified recombinant human Akt kinase was monitored for kinase activity in the presence or absence of inhibitors in a 96-well format. Detection was d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2008
Entry Details Article
PubMed