BDBM24926 1-(3-chlorophenyl)-3-methyl-N-[(1S)-1-phenylethyl]-1H-pyrazolo[4,3-c]pyridin-6-amine::BMCL185648 Compound 15::pyrazolopyridine-based compound, 2

SMILES C[C@H](Nc1cc2n(nc(C)c2cn1)-c1cccc(Cl)c1)c1ccccc1

InChI Key InChIKey=NTAIRXFACXVUQO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24926   

TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24926(1-(3-chlorophenyl)-3-methyl-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50: 121nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2008
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Sunesis Pharmaceuticals

LigandPNGBDBM24926(1-(3-chlorophenyl)-3-methyl-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50: 121nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2008
Entry Details Article
PubMed