BDBM2494 (+/-)-4-Hydroxy.6-phenyl-3-[phenyl(phenylthio)methyl]-2H-pyran-2-one::4-hydroxy-6-phenyl-3-[phenyl(phenylsulfanyl)methyl]-2H-pyran-2-one::4-hydroxy-6-phenyl-pyranylthiomethane 24::C-3-substituted Pyran-2-one 3

SMILES Oc1cc(oc(=O)c1C(Sc1ccccc1)c1ccccc1)-c1ccccc1

InChI Key InChIKey=LVOUHVQQFFTPTD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2494   

TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2494((+/-)-4-Hydroxy.6-phenyl-3-[phenyl(phenylthio)meth...)
Affinity DataIC50: 780nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2004
Entry Details Article
PubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Parke-Davis Pharmaceutical Research

LigandPNGBDBM2494((+/-)-4-Hydroxy.6-phenyl-3-[phenyl(phenylthio)meth...)
Affinity DataIC50: 780nMpH: 4.7 T: 2°CAssay Description:For determination of IC50 values, HIV-1 protease was added to assay buffer containing inhibitor and the substrate (H-His-Lys-Ala-Arg-Val-Leu- (p-NO2)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2004
Entry Details Article
PubMed