BDBM25000 4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1H-imidazo[4,5-c]pyridin-2-yl]-1,2,5-oxadiazol-3-amine::oxadiazole-containing compound, 11c

SMILES CCn1c(nc2c(ncc(OCCCN)c12)-c1cc[nH]c1)-c1nonc1N

InChI Key InChIKey=BFFORFSCMCLHMJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25000   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Glaxosmithkline

LigandPNGBDBM25000(4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1...)
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2008
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Glaxosmithkline

LigandPNGBDBM25000(4-[7-(3-aminopropoxy)-1-ethyl-4-(1H-pyrrol-3-yl)-1...)
Affinity DataIC50: 126nMAssay Description:IC50 is the inhibitor concentration, which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from radiolabeled AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2008
Entry Details Article
PubMed