BDBM251882 US9475806, 12-D

SMILES COc1cc(C)c2[nH]ccc2c1C(C)(C)c1nc2cc(cnc2[nH]1)C#N

InChI Key InChIKey=RCFXHYBGKNUDMF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 251882   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM251882(US9475806, 12-D)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Recombinant human factor B (expressed in drosophila cells and purified using standard methods) labeled with biotin (10 nM), europium-labeled streptav...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/25/2017
Entry Details
Go to US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM251882(US9475806, 12-D)
Affinity DataIC50: 30nMAssay Description:Displacement of Cy5 from recombinant human biotin-labeled factor B expressed in drosophila cells after 2 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed