BDBM25247 N-(2-aminophenyl)-4-(1-benzylpiperidin-4-yl)benzamide::benzamide derivative, 8d

SMILES Nc1ccccc1NC(=O)c1ccc(cc1)C1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=ITRKUDJHKGMANV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25247   

TargetHistone deacetylase 1(Human)
Astrazeneca

LigandPNGBDBM25247(N-(2-aminophenyl)-4-(1-benzylpiperidin-4-yl)benzam...)
Affinity DataIC50: 45nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed