BDBM25255 N-(2-aminophenyl)-4-(1-{[4-(methylcarbamoyl)phenyl]methyl}piperidin-4-yl)benzamide::benzamide derivative, 16e

SMILES CNC(=O)c1ccc(CN2CCC(CC2)c2ccc(cc2)C(=O)Nc2ccccc2N)cc1

InChI Key InChIKey=PPIFUYCFGJGTGQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25255   

TargetHistone deacetylase 1(Human)
Astrazeneca

LigandPNGBDBM25255(N-(2-aminophenyl)-4-(1-{[4-(methylcarbamoyl)phenyl...)
Affinity DataIC50: 31nMpH: 8.0 T: 2°CAssay Description:The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Affinity purified recombinant HDAC1 enzyme was incubated with acetylated histone H4 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed