BDBM252850 US9464076, 2::US9464076, 3::US9464076, 4::US9464076, 5::US9464076, 6

SMILES CC(=O)c1ccc(C(C)=O)c2c(C)c(sc12)C(=O)Nc1cc(c2ccccc2n1)C(C)(C)O

InChI Key InChIKey=QPLUHPHEDFKQDX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 252850   

LigandPNGBDBM252850(US9464076, 2 | US9464076, 6 | US9464076, 4 | US946...)
Affinity DataIC50: 2.60nMpH: 7.5 T: 2°CAssay Description:A human acute lymphoblastic lymphoma T cell line MOLT-4 (which can be purchased under ATCC No. CRL-1582 from ATCC) was cultured in an RPMI1640 medium...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

LigandPNGBDBM252850(US9464076, 2 | US9464076, 6 | US9464076, 4 | US946...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human MOLT4 cell-derived PDE10A using [3H]cAMP as substrate measured after 2 hrs in presence of rolipram/milrinone by topcount methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM252850(US9464076, 2 | US9464076, 6 | US9464076, 4 | US946...)
Affinity DataIC50: 5.10nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

LigandPNGBDBM252850(US9464076, 2 | US9464076, 6 | US9464076, 4 | US946...)
Affinity DataIC50: 5.80nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

LigandPNGBDBM252850(US9464076, 2 | US9464076, 6 | US9464076, 4 | US946...)
Affinity DataIC50: 5.90nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent

LigandPNGBDBM252850(US9464076, 2 | US9464076, 6 | US9464076, 4 | US946...)
Affinity DataIC50: 11nMpH: 7.5Assay Description:Inhibitory activity-1 assay: To a solution containing 20 mM Tris-HCl (pH 7.5), 1 mM MgCl2, 100 μM EDTA, 330 μg/ml bovine serum albumin, 50 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2017
Entry Details
US Patent