BDBM25340 N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-{2-[2-(4-methylpiperazin-1-yl)-2-oxoacetamido]propan-2-yl}-6-oxo-1,6-dihydropyrimidine-4-carboxamide::N-methyl-pyrimidinone derivative, 16

SMILES CN1CCN(CC1)C(=O)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C

InChI Key InChIKey=DPAFVBVGSXRSSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25340   

TargetGag-Pol polyprotein(HIV-1)
Merck Research Laboratories

LigandPNGBDBM25340(N-[(4-fluorophenyl)methyl]-5-hydroxy-1-methyl-2-{2...)
Affinity DataIC50: 26nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2008
Entry Details Article
PubMed