BDBM253621 US9701672, 52

SMILES Fc1cc(OCCCC(F)(F)F)ccc1[C@@]1(CC(c2ccn(CC3CC3)n2)=C(c2nnn[nH]2)C(=O)N1)C(F)(F)F

InChI Key InChIKey=QUEJXKUYWMDCNQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 253621   

LigandPNGBDBM253621(US9701672, 52)
Affinity DataIC50: 3.20nMpH: 7.4Assay Description:The MGAT enzyme reactions were performed in Corning FALCON 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2018
Entry Details
Go to US Patent

LigandPNGBDBM253621(US9701672, 52)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
LigandPNGBDBM253621(US9701672, 52)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of mouse MGAT2 using 2-oleoylglycerol and oleoyl-coenzyme A as substrate by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed